卢喜科 张逊
【摘要】目的:探讨中心型非小细胞肺癌袖式肺叶切除与全肺切除的术式选择。方法:回顾总结87例袖式肺叶切除和325例全肺切除的中心型非小细胞肺癌手术切除病人的临床资料,术后生存率、术后并发症的发生率及术后生存质量,进行统计学分析。结果:非小细胞肺癌病例的袖式肺叶切除术后5年生存率为37.9%,全肺切除为24%。但在对I、II、III期病人进行分期对比中两组具有相似的术后生存率。袖式肺叶切相对于全肺切除有较低的术后死亡率(0% vs 8%)和较高的术后生存质量(11.4 vs 7.1),但III期病人有较高的术后局部复发率(58.3% vs 11.2%)。结论:在中心型非小细胞肺癌需要选择袖式肺叶切除或全肺切除时,即使肺功能良好,I、II期病人也建议尽可能行袖式肺叶切除,而III期病人如果肺功能允许,建议行全肺切除。
【关键词】:非小细胞肺癌 袖式肺叶切除 全肺切除
Sleeve lobectomy compared to pneumonectomy for the treatment of non-small cell lung cancer
LU Xike ZHANG Xun Department of thoracic, Tianjin chest hospital, TianJin (300051), China.
[Abstract] Objective: To investigate the surgical choice making, sleeve lobectomy versus pneumonectomy for patient with Central Type non-small cell Lung Cancer. Methods: We summarized the clinical data of 87 cases sleeve lobectomy and 325 cases of pneumonectomy. Their postoperative survival rate, the incidence of their postoperative complications and life quality have been statistically analyzed. Results: The overall 5-years suevival rate was 37.9% in the sleeve lobectomy(SL) and 24% in the pneumonectomy(PN). But SL is similar in survival rates with the PN for patients with NSCLC in differential compare with by stages I II or III. Patients with SL have comparatively low mortality (0% vs 8%)and high life quality (11.4 vs 7.1),but high incidence of local recurrence in patients with stage III. Conclusions: Our findings demonstrated that sleeve lobectomy would be favored for patients staged I and II. For patients with NSCLC in stage III, pneumonectomy should be recommended, provided their pulmonary function allowable.
【Keywords】: NSLC Sleeve lobectomy Pneumoinectomy
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作者单位:天津市胸科医院胸外科(300051)
通信地址:xike_lu@yahoo.com.cn



